- Sayler Park
- Sayre
- Scenic Ridge
- Schauers Acres
- Schenck
- Schlegels Grove
- Schley
- Schoenbrunn
- Schooley
- Schrader
- Schumm
- Science Hill
- Scienceville
- Scio
- Scioto
- Scioto Estates
- Scioto Furnace
- Scioto Meadows
- Scioto Run
- Scioto Village
- Sciotodale
- Sciotoville
- Scipio
- Scotch Ridge
- Scotland
- Scott
- Scott Corners
- Scottown
- Scotts Crossing
- Scroggsfield