- Sciotavale
- Sconnelltown
- Scot Run
- Scotch Hill
- Scotch Hollow
- Scotia
- Scotland
- Scotrun
- Scots Glen
- Scott
- Scott Center
- Scott Haven
- Scott Township
- Scottdale
- Scotts Crossing
- Scottsville
- Scottsville
- Scovell Island
- Scranton
- Scranton Corners
- Scullton
- Sea Right
- Seal
- Seamentown
- Seanor
- Searchs Island
- Searights
- Sebastopol
- Sebring
- Secane