- Eadytown
- Eagle Crest
- Eagle Island
- Eagle Point
- Earle
- Earles Grove
- Earlwood Park
- Early Branch
- Earlys Crossroads
- Easley
- East Gaffney
- East Gantt
- East Gate Village
- East Lake
- East Shore
- East Spartanburg
- East Sumter
- East View
- East View Estates
- Eastatoe
- Eastcliff
- Eastover
- Eastway Park
- Eau Claire
- Ebenezer
- Ebenezer
- Ebenezer
- Ebenezer
- Edenwood
- Edgefield