S
- (West Coast District Municipality) Swartwater
- (City of Cape Town) Sun Valley
- (Overberg District Municipality) Sunny Seas
- (City of Cape Town) Sunnycroft
- (City of Cape Town) Sunnyacres
- (Cape Winelands District Municipality) Suider-Paarl
- (Overberg District Municipality) Strandskloof
- (City of Cape Town) Strandfontein
- (City of Cape Town) Strand
- (West Coast District Municipality) Stompneusbaai
- (City of Cape Town) Steenbras
- (City of Cape Town) Steenberg
- (City of Cape Town) Steelwater
- (West Coast District Municipality) Sandberg
- (Cape Winelands District Municipality) Spes Bona
- (Cape Winelands District Municipality) Spes Bona
- (Overberg District Municipality) Speelmansrivier
- (City of Cape Town) Sonstraal
- (Cape Winelands District Municipality) Slanghoek
- (Cape Winelands District Municipality) Skerpenhevwel
- (City of Cape Town) Saxonsea
- (Overberg District Municipality) Silver Sands
- (City of Cape Town) Silver Sands
- (City of Cape Town) Scottsville
- (City of Cape Town) Scarborough
- (West Coast District Municipality) Sauer
- (Cape Winelands District Municipality) Saron
- (Cape Winelands District Municipality) Sandrivier
- (Cape Winelands District Municipality) Sandhills
- (Overberg District Municipality) Stanford