- Ponce de Leon
- Pond
- Ponder
- Pondfork
- Pontiac
- Poole Ford
- Poplar Bluff
- Port Hudson
- Portage Des Sioux
- Portage Island
- Portageville
- Porter
- Portia
- Portland
- Possum Trot
- Possum Walk
- Post Oak
- Postal
- Potosi
- Pottersville
- Potts
- Powe
- Powell
- Powellville
- Powers Island
- Powersite
- Powersville
- Poynor
- Prairie City
- Prairie Hill