- San Luis
- Sand Hill
- Sandals
- Sandstone
- Sandy Hook
- Sandy Island
- Sandywoods Township
- Sank
- Santa Fe
- Santa Rosa
- Santiago
- Santuzza
- Sapp
- Sappington
- Saratoga
- Sarcoxie
- Sargent
- Sargent
- Sarvis Point
- Saunders
- Savannah
- Saverton
- Sawyer
- Saxton
- Scearces
- Schell City
- Schlatitz
- Schluersburg
- Schmidts Island
- Schmitt Ford