- Sharpsburg
- Shaver Ford
- Shaw
- Shaw
- Shawan
- Shawne
- Shawnee Mound
- Shawneetown
- Sheil
- Shelbina
- Shelby
- Shelby
- Shelbyville
- Sheldon
- Shell Knob
- Shelton Ford
- Shepherd of the Hills Estates
- Sheridan
- Sherman
- Sherrill
- Shibboleth
- Shibleys Point
- Shirley
- Shoal
- Shoal Creek Drive
- Shoal Creek Estates
- Shook
- Short Bend
- Shott
- Shoveltown