- Schroon Lake
- Schultzville
- Schuyler Falls
- Schuyler Heights
- Schuyler Island
- Schuyler Lake
- Schuylerville
- Schuylerville
- Scidmore Woods
- Scio
- Sciola
- Scipio Center
- Scipioville
- Sconondoa
- Scotch Bonnet Island
- Scotch Bush
- Scotch Church
- Scotch Hill
- Scotch Pine Manor Mobile Home Park
- Scotchbrush
- Scotchtown
- Scotia
- Scott
- Scotts Corner
- Scotts Corners
- Scottsburg
- Scottsville
- Scout Island
- Scow Island
- Scranton